abstract：CONTEXT:Adenocarcinoma in situ of the cervix is a recently recognized interpretation in the Bethesda 2001 system. Although specific morphologic criteria have been published, recognizing this entity is still difficult. OBJECTIVE:To compare pathologists' ability to correctly identify and categorize adenocarcinoma in sit...

journal_title：Archives of pathology & laboratory medicine

authors： Renshaw AA,Mody DR,Lozano RL,Volk EE,Walsh MK,Davey DD,Birdsong GG

更新日期：2004-02-01 00:00:00

abstract：CONTEXT:Success in the practice of pathology demands proficiency in management, but management training for pathology residents is generally inadequate, with little agreement on an appropriate curriculum or competency assessment. Most residency training programs do not have faculty members who are interested and have e...

journal_title：Archives of pathology & laboratory medicine

authors： Horowitz RE,Naritoku W,Wagar EA

更新日期：2004-01-01 00:00:00

abstract：:We report a case of an intraocular inflammatory myofibroblastic tumor nearly filling the vitreous cavity of the eye of a 50-year-old man. The tumor was composed of a mixture of spindle cells and mixed inflammatory elements, including numerous plasma cells. The differential diagnosis included inflammatory pseudotumor a...

journal_title：Archives of pathology & laboratory medicine

authors： O'Malley DP,Poulos C,Czader M,Sanger WG,Orazi A

更新日期：2004-01-01 00:00:00

abstract：CONTEXT:Fish consumption has been associated with a decreased risk of coronary artery disease. Recent studies have illustrated that the high mercury content in cold-water fish may negate the cardiovascular benefits of fish meals. Fish oils have similar antiatherogenic properties to fish, and similar studies should be p...

journal_title：Archives of pathology & laboratory medicine

authors： Foran SE,Flood JG,Lewandrowski KB

更新日期：2003-12-01 00:00:00

abstract：CONTEXT:Lipochoristomas (lipomatous choristomas) are rare tumors of the acoustic nerve (cranial nerve VIII/vestibulocochlear nerve) within the internal acoustic canal and sometimes the cerebellopontine angle, and are histogenetically believed to be congenital malformations. Their clinically indolent behavior has recent...

journal_title：Archives of pathology & laboratory medicine

authors： Wu SS,Lo WW,Tschirhart DL,Slattery WH 3rd,Carberry JN,Brackmann DE

更新日期：2003-11-01 00:00:00

abstract：:We describe a case of adenomatous polyp of the colon that harbored small foci of signet ring cell carcinoma. The patient was a 64-year-old woman with end-stage renal disease and sepsis who underwent colonoscopy to evaluate the possibility of pseudomembranous colitis. A polyp was found incidentally in the right colon a...

journal_title：Archives of pathology & laboratory medicine

authors： Bismar TA,Maluf H,Wang HL

更新日期：2003-11-01 00:00:00

abstract：:Carcinoembryonic antigen (CEA) is recommended as a serologic marker to monitor colorectal carcinoma recurrence. Elevations of CEA due to causes other than carcinoma exist and may lead to a misdiagnosis of recurrent carcinoma. We report a case of bowel sequestration with mucocele formation at the site of previous colo-...

journal_title：Archives of pathology & laboratory medicine

authors： Haber MM,Leon ME,Bakker JE,Nagle D

更新日期：2003-10-01 00:00:00

abstract：CONTEXT:Most posttransplantation lymphoproliferative disorders (PTLDs) are associated with Epstein-Barr virus (EBV) infection. The EBV latent membrane protein 1 (LMP-1) is important in the transformation of B lymphocytes through its interaction with intracellular tumor necrosis factor receptor-associated factors (TRAFs...

journal_title：Archives of pathology & laboratory medicine

authors： Ramalingam P,Chu WS,Tubbs R,Rybicki L,Pettay J,Hsi ED

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:To review the advances in clinically useful molecular biologic techniques and to identify their applications in clinical practice, as presented at the 11th Annual William Beaumont Hospital DNA Symposium. DATA SOURCES:The 8 manuscripts submitted were reviewed, and their major findings were compared with liter...

journal_title：Archives of pathology & laboratory medicine

authors： Kiechle FL,Holland-Staley CA

更新日期：2003-09-01 00:00:00

abstract：:Sarcoidosis is a chronic systemic disease of unknown etiology, which is characterized by noncaseating epitheloid granulomas usually in multiple organs. Here we describe changes in cytokine mRNA expression by peripheral blood mononuclear cells (PBMCs) and changes of cytokine protein levels in plasma over a time course ...

journal_title：Archives of pathology & laboratory medicine

authors： Schoppet M,Pankuweit S,Maisch B

更新日期：2003-09-01 00:00:00

abstract：CONTEXT:The discovery that recurrent chromosomal translocations are involved in the pathogenesis of non-Hodgkin lymphomas has greatly improved our understanding of these diseases and revolutionized their diagnosis. OBJECTIVE:To review the mechanisms by which chromosomal translocations occur and contribute to the patho...

journal_title：Archives of pathology & laboratory medicine

authors： Vega F,Medeiros LJ

更新日期：2003-09-01 00:00:00

abstract：:Laboratories contemplating either the addition of new molecular tests or modifying methods approved by the Food and Drug Administration for human papillomavirus testing should be aware of a variety of procedural, performance, and regulatory issues surrounding such activity. Diagnostic medical laboratory testing in the...

journal_title：Archives of pathology & laboratory medicine

authors： Seabrook JM,Hubbard RA

更新日期：2003-08-01 00:00:00

abstract：:Multiple lymphomatous polyposis (MLP) is an uncommon type of primary non-Hodgkin gastrointestinal (GI) B-cell lymphoma characterized by the presence of multiple polyps along the GI tract. Malignant cells of MLP have mantle cell characteristics and thus are considered to be the counterpart of the mantle cell lymphoma (...

journal_title：Archives of pathology & laboratory medicine

authors： Remes-Troche JM,De-Anda J,Ochoa V,Barreto-Zuñiga R,Arista-Nasr J,Valdovinos MA

更新日期：2003-08-01 00:00:00

abstract：CONTEXT:The cause for intrauterine fetal demise (IUFD) occurring in early gestation in a high percentage of spontaneous abortions is unknown. OBJECTIVE:To determine the association, if any, of umbilical cord abnormalities with early IUFD. DESIGN:All cases of IUFD occurring within 16 weeks of gestation that presented ...

journal_title：Archives of pathology & laboratory medicine

authors： Singh V,Khanum S,Singh M

更新日期：2003-07-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is a neoplastic proliferation of Langerhans cells that occurs in a range of nodal and extranodal sites. Scattered reports of LCH within the thymus exist, typically among children within the setting of multifocal, multisystem disease. Rare cases of isolated LCH involving the thymus h...

journal_title：Archives of pathology & laboratory medicine

authors： Lee BH,George S,Kutok JL

更新日期：2003-07-01 00:00:00

abstract：CONTEXT:In the normal course of activity, pathologists create and archive immense data sets of scientifically valuable information. Researchers need pathology-based data sets, annotated with clinical information and linked to archived tissues, to discover and validate new diagnostic tests and therapies. Pathology recor...

journal_title：Archives of pathology & laboratory medicine

authors： Berman JJ

更新日期：2003-06-01 00:00:00

abstract：:Toxoplasmosis is a common opportunistic pathogen in patients with acquired immunodeficiency syndrome (AIDS). It usually presents with ocular, central nervous system, or pulmonary disease. Gastric toxoplasmosis is uncommon in AIDS patients, especially in the absence of central nervous system manifestations. In the few ...

journal_title：Archives of pathology & laboratory medicine

authors： Ganji M,Tan A,Maitar MI,Weldon-Linne CM,Weisenberg E,Rhone DP

更新日期：2003-06-01 00:00:00

abstract：CONTEXT:The pathogenesis of appendicitis remains poorly understood. Despite new diagnostic techniques, appendices removed from patients with suspected appendicitis often appear histologically normal on conventional examination. There is increasing evidence of involvement of the enteric nervous system in immune regulati...

journal_title：Archives of pathology & laboratory medicine

authors： Nemeth L,Rolle U,Reen DJ,Puri P

更新日期：2003-05-01 00:00:00

abstract：:Intracellular inclusions in lymphoproliferative disorders are not common. Multiple different types of inclusions have been reported in chronic lymphocytic leukemia (CLL), including vacuoles, crystals, and pseudocrystals. Most of the reported cases were seen in the bone marrow lymphocytes, and the majority of these on ...

journal_title：Archives of pathology & laboratory medicine

authors： Dorion RP,Shaw JH

更新日期：2003-05-01 00:00:00

abstract：CONTEXT:Solitary fibrous tumors (SFTs) of the central nervous system are rare neoplasms that usually present as dura-based masses and clinically resemble meningiomas. Histologically, they can be similar to fibrous meningioma or hemangiopericytoma (HPC). In particular, densely cellular regions seen in some SFTs can be i...

journal_title：Archives of pathology & laboratory medicine

authors： Tihan T,Viglione M,Rosenblum MK,Olivi A,Burger PC

更新日期：2003-04-01 00:00:00

abstract：:Although atrial myxoma is the most common primary tumor of the heart, the synchronous occurrence of myxomas of the intestine and the heart has not been reported in the English literature. We report a case of a 47-year-old woman who presented with small bowel obstruction by a pedunculated mass that was found to be a my...

journal_title：Archives of pathology & laboratory medicine

authors： Wang Y,Sharkey FE

更新日期：2003-04-01 00:00:00

abstract：:Multiple pulmonary leiomyomatous hamartomas (MPLHs) are extremely rare lesions. We present a case of MPLHs associated with a bronchogenic cyst in a symptomless, 46-year-old man. Previously, MLPHs have been reported to occur in men; therefore, not all cases of MPLHs represent metastases from a uterine smooth muscle tum...

journal_title：Archives of pathology & laboratory medicine

authors： Nistal M,Hardisson D,Riestra ML

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:To identify the sources of analytical variation for cyclosporine and tacrolimus in a 3-year longitudinal study. DESIGN:Two pools of whole blood were spiked with cyclosporine and tacrolimus, respectively. One aliquot of cyclosporine and 2 of the tacrolimus pool were distributed in the first and last mailing f...

journal_title：Archives of pathology & laboratory medicine

authors： Steele BW,Wang E,Soldin SJ,Klee G,Elin RJ,Witte DL,College of American Pathologists Study.

更新日期：2003-03-01 00:00:00

abstract：:Context.-We investigated expression of the adhesion molecule CD31 in sinus histiocytosis with massive lymphadenopathy (SHML) and Langerhans cell histiocytosis (LCH) because (1) SHML and LCH cells express a variety of cellular adhesion molecules and (2) SHML has been characterized as a reactive histiocytic proliferatio...

journal_title：Archives of pathology & laboratory medicine

authors： Slone SP,Fleming DR,Buchino JJ

更新日期：2003-03-01 00:00:00

abstract：:Neuroendocrine differentiation has been reported in both in situ and infiltrating breast cancers. The prognostic significance of neuroendocrine differentiation in mammary carcinoma is unclear. We report a case of infiltrating ductal carcinoma in which there was a morphologically conventional-appearing infiltrating duc...

journal_title：Archives of pathology & laboratory medicine

authors： David O,Bhattacharjee M

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:To examine the hypothesis that older hospitalized patients have higher laboratory costs than younger patients in the same severity-adjusted diagnosis-related group (DRG). DESIGN:We obtained hospital case mix data sets (1995-1997) from the Massachusetts Division of Health Care Finance and Policy. We selected ...

journal_title：Archives of pathology & laboratory medicine

authors： Brimhall BB,Dean T,Hunt EL,Siegrist RB,Reiquam W

更新日期：2003-02-01 00:00:00

abstract：:We report a large cell neuroendocrine carcinoma arising in the ampulla of Vater. The patient, a 74-year-old woman, presented with a 3-cm ulcerated mass located in the ampullary region. She died of disease 8 months after surgery. Microscopically, the tumor was extensively necrotic. It was composed of islands and trabec...

journal_title：Archives of pathology & laboratory medicine

authors： Cavazza A,Gallo M,Valcavi R,De Marco L,Gardini G

更新日期：2003-02-01 00:00:00

abstract：:Pathologic examination of an excisional biopsy specimen of a subepidermal nodule from the nasal tip of a 37-year-old black man demonstrated papillae covered by eosinophilic columnar epithelial cells, suggesting cylindric cell papilloma or well-differentiated papillary adenocarcinoma of nasal mucosa. The patient did no...

journal_title：Archives of pathology & laboratory medicine

authors： Smith FB,Shemen LJ,Guerrieri C,Ismail SS

更新日期：2003-02-01 00:00:00

abstract：CONTEXT:Although high-grade vulvar intraepithelial neoplasia (VIN III) is a clinically significant lesion, it can be overlooked because of nonspecific clinical findings and the fact that its cytomorphologic features mimic those of mild cervical intraepithelial neoplasia (CIN I). OBJECTIVE:To determine if there are cyt...

journal_title：Archives of pathology & laboratory medicine

authors： August CZ,Ganji M,Froula E

更新日期：2003-01-01 00:00:00

abstract：:Benign heterotopic epithelial inclusions in axillary lymph nodes are an extremely rare condition that must be differentiated from metastatic carcinoma. We describe 2 histologically different examples of benign epithelial inclusions in nonsentinel axillary lymph nodes, each with an unusual clinical presentation. ...

journal_title：Archives of pathology & laboratory medicine

authors： Resetkova E,Hoda SA,Clarke JL,Rosen PP

更新日期：2003-01-01 00:00:00

abstract：CONTEXT:Quantitation of hemoglobin (Hb) A(1c) and investigation of hemoglobinopathy on the Bio-Rad Variant analyzers require a switch between 2 separate kits that is time consuming and causes errors. OBJECTIVE:Evaluation of a new Variant II HbA(2)/HbA(1c) Dual kit capable of both Hb A(1c) quantitation and hemoglobinop...

journal_title：Archives of pathology & laboratory medicine

authors： Lafferty JD,McFarlane AG,K Chui DH

更新日期：2002-12-01 00:00:00

abstract：:Considering the variety of aberrant locations in which ectopic parathyroid adenomas may be found, these neoplasms can be difficult to identify and treat surgically. The results of radiographic and cytologic studies may lead to confusion of these neoplasms with lesions of thyroid origin. We present a case of an ectopic...

journal_title：Archives of pathology & laboratory medicine

authors： Pitsilos SA,Weber R,Baloch Z,LiVolsi VA

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:To review the current understanding of the pathophysiology of antithrombin deficiency and its role in congenital thrombophilia. Recommendations for diagnostic testing of antithrombin function and concentration, derived from the medical literature and consensus opinions of recognized experts in the field, are ...

journal_title：Archives of pathology & laboratory medicine

authors： Kottke-Marchant K,Duncan A

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVES:To review the state of the art relating to elevated hemostatic factor levels as a potential risk factor for thrombosis, as reflected by the medical literature and the consensus opinion of recognized experts in the field, and to make recommendations for the use of specific measurements of hemostatic factor le...

journal_title：Archives of pathology & laboratory medicine

authors： Chandler WL,Rodgers GM,Sprouse JT,Thompson AR

更新日期：2002-11-01 00:00:00

abstract：CONTEXT:Three levels of histologic sections are routinely prepared for small biopsies in many surgical pathology laboratories. The first level is superficial and may not be representative of the entire biopsy, and may therefore represent wasted resources and time for technologists and pathologists alike. OBJECTIVE:To ...

journal_title：Archives of pathology & laboratory medicine

authors： Luo YV,Prihoda TJ,Sharkey FE

更新日期：2002-10-01 00:00:00

abstract：CONTEXT:Fear that damaging information from autopsy may be introduced as evidence in lawsuits alleging medical malpractice is often cited as one factor contributing to the decline in autopsy rates. OBJECTIVE:To determine how autopsy information influences the outcome of medical malpractice litigation. DESIGN:We studi...

journal_title：Archives of pathology & laboratory medicine

authors： Bove KE,Iery C,Autopsy Committee, College of American Pathologists.

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:To investigate ras gene alteration in human gastric adenocarcinomas and its potential relationship to ras signal transduction mediators. DESIGN:Genomic DNA from 104 gastric tumors were analyzed by sequencing of polymerase chain reaction-amplified products for the presence of ras mutations. All the samples we...

journal_title：Archives of pathology & laboratory medicine

authors： Yoo J,Park SY,Robinson RA,Kang SJ,Ahn WS,Kang CS

更新日期：2002-09-01 00:00:00

abstract：CONTEXT:Constipation or recurrent intestinal dysmotility problems are common after definitive surgical treatment in Hirschsprung disease (HD). c-Kit-positive interstitial cells of Cajal (ICCs) play a key role in the motility function and development of the gastrointestinal tract. Interstitial cells of Cajal that carry ...

journal_title：Archives of pathology & laboratory medicine

authors： Rolle U,Piotrowska AP,Nemeth L,Puri P

更新日期：2002-08-01 00:00:00

abstract：:Hibernomas are rare neoplasms composed of brown adipose tissue. The behavior of these neoplasms has been described as uniformly benign in humans. The only recurrence cited in the English literature involved a sarcoma with hibernoma-like features, which was reported in abstract form. We present 2 cases of hibernoma, on...

journal_title：Archives of pathology & laboratory medicine

authors： Lele SM,Chundru S,Chaljub G,Adegboyega P,Haque AK

更新日期：2002-08-01 00:00:00

abstract：CONTEXT:Identification of patients is one of the first steps in ensuring the accuracy of laboratory results. In the United States, hospitalized patients wear wristbands to aid in their identification, but wristbands errors are frequently found. OBJECTIVE:To investigate if continuous monitoring of wristband errors by p...

journal_title：Archives of pathology & laboratory medicine

authors： Howanitz PJ,Renner SW,Walsh MK

更新日期：2002-07-01 00:00:00